Sceletium SCE™ Extract

Sceletium Tortuosium is often referred to as a sacred plant that has been used by the San and Khoikhoi people of Southern Africa for hundreds of years. It has incredible human benefits that are just beginning to be realized, including being one of the most natural and powerful anti-anxiety factors and a highly effective natural anti-depressant.
Sceletium Tortuosum is a natural and effective selective serotonin re-uptake inhibitor (SSRI). The mood elevating action of sceletium tortuosum is caused by several alkaloids including mesembrine, mesembrenol and tortuosamine which interact with the brain’s dopamine and serotonin receptors. Mesembrine is a major alkaloid present in sceletium tortuosum and has been demonstrated to be a potent serotonin re-uptake inhibitor and serotonin releasing agent.
Modern research now supports the efficacy of this traditionally discovered extract for enhancing positive mood and cognitive function, reducing stress, and inducing calm without sedative effects, and, very importantly, without inducing dependency. It is non-habit forming and non-addictive.
Sceletium tortuosum binds to serotonin transporters, inhibiting re-uptake of this neurotransmitter from the synapse of serotonergic neurons, resulting in an increased serotonin concentration in the synaptic cleft, in the same fashion as prescription SSRIs.
Sceletium blocks the reabsorption (re-uptake) of serotonin into neurons. This makes more serotonin available to improve transmission of messages between neurons. SSRIs are called selective because they mainly affect serotonin, not other neurotransmitters.)
The major alkaloid in our own Sceletium extract is mesembrine and it is the predominant serotonin re-uptake inhibitor.
With our Sceletium extraction, we take great care to produce an extract of +/- 3.5% alkaloids with at least 1% + Mesembrine content.
Our sceletium extract is produced from our very own sceletium tortuosum, which is a high quality variant native to southern Africa.